如何研究血小板的功能?一個重要手段就是體內清除血小板,靶點科技攜手德國Emfret,常備現貨,推出血小板清除抗體,貨號R300抗體,Antibodies for Mouse Platelet Depletion。如果4 µg抗體/g動物體重,可以持續更長時間。注射后60分鐘內可以去除血小板95%以上,建議每次注射100-200µL抗體(用無菌PBS稀釋)。詳情聯系靶點科技技術支持。
Specificity: R300抗體,Antibodies for Mouse Platelet Depletion.This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIbα(CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice. Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology.
清除原理:該抗體制劑含有針對小鼠 GPIbα(CD42b) 的純化大鼠單克隆抗體的混合物。用二價 IgG 靶向該受體導致小鼠嚴重且不可逆的 Fc 非依賴性血小板耗竭。血小板耗竭常用于研究血小板在(病理)生理學中的一般作用。
血小板的功能: