BroadPharm品牌的疊氮基-PEG4-NHS酯是一種非常受歡迎的PEG試劑,含有疊氮化物基團和NHS酯。親水性PEG墊片增加了在水性介質中的溶解度。疊氮化物基團可以通過Click Chemistry與炔烴、BCN、DBCO反應,產生穩定的三唑鍵。NHS 酯可用于標記蛋白質、胺修飾寡核苷酸和其他含胺分子的伯胺 (-NH2)。試劑級,用于研究目的。請聯系Broadpharm代理靶點科技進行GMP級查詢。
Azido-PEG4-NHS ester is a very popular PEG reagent which containan azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
部分參考文獻
1. Hull SM, Lindsay CD, et al 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials. 2021. 31(7). 2007983
2. Mapes, J. H., Stover, J., Stout, H. D., Folsom, T. M., Babcock, E., Loudwig, S., ... & Swaminathan, J. (2023). Robust and scalable single-molecule protein sequencing with fluorosequencing. bioRxiv, 2023-09.
BroadPharm是一家總部位于圣地亞哥的生物技術公司,以客戶為中心。公司專注于為全球客戶提供高質量的PEG接頭、Click Chemistry試劑、ADC接頭、PROTAC接頭、藥物遞送脂質、核苷、亞磷酰胺和標記試劑。BroadPharm成立于2009年,生產超過2000種分散的、高純度的聚乙二醇(PEG)試劑,目前這些PEG試劑被廣泛應用于生物偶聯、抗體-藥物偶聯(ADC)治療、藥物遞送以及診斷領域。具體訂購,可以聯系授權代理商BroadPharm代理靶點科技。